Langerhans Cell Histiocytosis: An Illusion of Hope

نویسندگان

  • Vela D Desai
  • Smita R Priyadarshinni
  • Beena Varma
  • Rajeev Sharma
چکیده

INTRODUCTION Langerhans cell histiocytosis (LCH) is a rare atypical cellular disorder characterized by clonal proliferation of Langerhans cells leading to myriad clinical presentations and variable outcomes. It usually occurs in children and young adults. It can be present with local and systemic manifestation involving skin, bone, mucosal tissues and internal organs. AIMS AND OBJECTIVES The stomatologist plays an important role in management of the disease by keeping in mind the various oral manifestations of the disease. CASE REPORT Of a child with disseminated LCH with multiorgan involvement who presented with failure to thrive, osteolytic bony lesions and extensive cutaneous eruptions. CONCLUSION Early diagnosis and awareness is necessary to treat the patients. How to cite this article: Desai VD, Priyadarshinni SR, Varma B, Sharma R. Langerhans Cell Histiocytosis: An Illusion of Hope. Int J Clin Pediatr Dent 2013;6(1):66-70.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Langerhans cell Histiocytosis: Seborrheic dermatitis-like skin signs and polypoid lesion of external ear in a 41-year-old man (Case report)

Langerhans cell histiocytosis includes a broad spectrum of clinical diseases resulted from proliferation and tissue infiltration of differentiated langerhans cells. This term includes Letterer-siwe disease, Hand-Schuller-Christian disease, eosinophilic granuloma and congenital reticulohistiocytosis that are more common in children than adults. This entity has recently been classified into restr...

متن کامل

Langerhans cell Histiocytosis: Report of a case with cutaneous lesions with favorable response to oral Thalidomide

We report of a 29-year-old man presented with yellow-red, scaling papules on the skin of scalp, retro-auricular folds, inguinal, axillary, chest and abdomen. The lesions had a poikilodermatious appearance in some areas, such as trunk. The patient also had diabetes insipidus and skull osteolytic lesions. The diagnosis of langerhans cell histiocytosis (LCH) was suggested based on H and E staining...

متن کامل

Indeterminate cell histiocytosis: a case report

Indeterminate cell histiocytosis is a very rare proliferative disorderof histiocytes which displays both langerhans cell histiocytosisand non langerhans cell histiocytosis immunophenotypic features.The majority of the patients develop multiple lesions which areclinically indistinguishable from generalized eruptive histiocytosis.We report a 14-year-old girl with multiple papules on the face,scal...

متن کامل

Langerhans cell histiocytosis of the clavicle in a 10-years-old girl

Langerhans cell histiocytosis (LCH) is an abnormal proliferation of Langerhans cells in one or more organs; bone is the most frequently involved organ in which the skull is the most frequent .The clavicle is rarely the primary site of the LCH, thereby the timely diagnosis is often delayed and most of the patients are primarily treated for acute or chronic osteomyelitis. Herein we report a 10 ye...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 6  شماره 

صفحات  -

تاریخ انتشار 2013